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Clinical pitfalls and serological diagnostics of MuSK myasthenia gravis

2023

This article focuses on the clinical pitfalls and blood tests for MUSK antibodies in MG. The study aimed to evaluate the diagnostic accuracy of enzyme-linked immunosorbent assay (ELISA) for anti-MuSK antibody in 160 patients with negative bloodwork to Achr antibodies who had generalized MG. They found that the ELISA test for detecting anti-MuSK antibodies was reliable and matched the results of other tests. The study also emphasized the challenges in diagnosing MuSK MG due to its unique symptoms and suggested that the ELISA test could be helpful in diagnosing this condition in clinical settings.

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